Cinnamoylbenzene → 3,4,6-Triphenyloxan-2-one

Participants

Reaction Steps

20.8 g (0.1 mol) of chalcone (1,3-diphenyl 1-propenone) are dissolved hot in 12.0 g (0.102 mol) of benzyl cyanide. 60 ml of hexane-absolute alcohol mixture (20-80) are added; the reaction medium is cooled to 0° C. in an ice-salt mixture. The catalyst (8 ml of 2 N ethanol KOH) is then added slowly. Crystallisation intervenes very quickly in the vessel, about 1 hour after the beginning of pouring which lasts 3/4 of an hour. The vessel is then placed in the refrigerator for the night.

Provenance & Evidence