化工社化工社 化学情報印刷レポート · 研究参考用
3',5'-Dichloro-2'-hydroxyacetophenone → 2,4-Dichloro-6-(1'-hydroxyethyl)phenol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3',5'-Dichloro-2'-hydroxyacetophenone | HCID 520608 | — |
| 反応物 | Sodium borohydride | HCID 4311764 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 2,4-Dichloro-6-(1'-hydroxyethyl)phenol | HCID 21162831 | 79.2% |
反応手順
3,5-Dichloro-2-hydroxyacetophenone (40 g) was treated in ethanol with sodium borohydride (4 g). The solid reaction product was recrystallized from benzene to give 2,4-dichloro-6-(1'-hydroxy ethyl) phenol (32 g, m.p. 70°).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04163801 |
| 出典データセット | uspto-grants-1979_08 |
| ORD ID | ord-d39073fcbf1340ba818bad721d4826bf |
| 出典メモ | uspto-grants-1979_08 |