Sodium borohydride → HCID 21162833, compound

HRID 261046Notes

Reaction equation

HRID 261046 reaction equation
[BH4-].[Na+].[Cl:3][C:4]1[CH:9]=[C:8]([C:10](=[O:12])[CH3:11])[C:7]([OH:13])=[C:6]([C:14](=[O:16])[CH3:15])[CH:5]=1>>[OH:16][CH:14]([C:6]1[CH:5]=[C:4]([Cl:3])[CH:9]=[C:8]([CH:10]([OH:12])[CH3:11])[C:7]=1[OH:13])[CH3:15]

Participants

3

Reactant 2

HCID 4311764Sodium borohydrideHCID 21162834HCID 21162834, compound

Product 1

HCID 21162833HCID 21162833, compound

Procedure

Sodium borohydride was added in small portions to a methanolic solution of 4-chloro-2,6-diacetylphenol (5 g) until the colour was completely discharged. The solvent was removed by distillation under reduced pressure to give a white solid which was washed with water and dilute hydrochloric acid. The product, 2,6-bis(1-hydroxyethyl)-4-chlorophenol, was obtained as a pale yellow gum (4.5 g).

Workup

  1. customThe solvent was removed by distillation under reduced pressure
  2. customto give a white solid which
  3. washwas washed with water and dilute hydrochloric acid

Sources & evidence

ORD record
ord-264ac5cf13084387b1e3b02ba71774ae
Source dataset
uspto-grants-1979_08
Patent number
US04163801

Reaction notes

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