反应详情

7.1 Parts of ethyl (4-formylphenoxy)-2,2-dimethylacetate described in U.S. Pat. No. 3,842,120 and 4.7 parts of acetophenone in 10 parts by volume of ethanol containing 0.01 part of sodium ethyl are reacted for 2 hours. This reaction mixture is quenched with 100 parts of cold water and extracted with ether. The ether extracts are dried over magnesium sulfate. Filtration of the magnesium sulfate, removal of the ether by evaporation at reduced pressure, and column chromatography on silica gel provides ethyl 2-[4-(2-benzoylethenyl)phenoxy]-2,2-dimethylacetate, melting at 68° to 70° C. This compound has the following structural formula ##STR5##

1. customThis reaction mixture is quenched with 100 parts of cold water
2. extractionextracted with ether
3. dry with materialThe ether extracts are dried over magnesium sulfate
4. filtrationFiltration of the magnesium sulfate, removal of the ether
5. customby evaporation at reduced pressure, and column chromatography on silica gel