HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 178484998, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 1-Cyano-2-methyl-3-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)isothiourea | HCID 103630 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178484998 | HCID 178484998 | — |
Reaction Steps
A solution of 75 ml of 33% methylamine in ethanol was added to a solution of 10.1 g of N-cyano-N'-[2-(5-methyl-4-imidazolylmethylthio)ethyl]-S-methylisothiourea in 30 ml of ethanol. The reaction mixture was set aside at ambient temperature for 2.5 hours. Following concentration under reduced pressure, the residue was recrystallized twice from isopropanol-petroleum ether to give N-cyano-N'-methyl-N"-[2-(5-methyl-4-imidazolylmethylthio)ethyl]guanidine, m.p. 141°-143°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04163858 |
| Source dataset | uspto-grants-1979_08 |
| ORD ID | ord-30e1b384fbd54af19cb8181ce1cfa339 |
| Source note | uspto-grants-1979_08 |