HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 70581408, compound → HCID 22808438, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 70581408 | HCID 70581408 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 22808438 | HCID 22808438 | — |
Reaction Steps
The above base, 1.1 g. (0.003 mol), on treatment with hydrogen chloride (anhydrous) in ethyl acetate, afforded the crude hydrochloride which after crystallization from ethyl acetate gave 1.2 g. (100%) of pure (-)-3-phenoxy-N-cyclobutylmethylmorphinan hydrochloride, m.p. 175°-177°, [α]D25 =-66.59° (c 1.03, MeOH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04163853 |
| Source dataset | uspto-grants-1979_08 |
| ORD ID | ord-da30ecba1de24124b1bf29c5a73bb780 |
| Source note | uspto-grants-1979_08 |