HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → 1-Benzyl-6-chloroimidazo[1,2-a]pyridinium bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | 6-Chloroimidazo(1,2-a)pyridine | HCID 2764328 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1-Benzyl-6-chloroimidazo[1,2-a]pyridinium bromide | HCID 20395573 | — |
Reaction Steps
A solution of 2.3 g. of 6-chloroimidazo[1,2-a]pyridine and 3.42 g. of α-bromotoluene in 40 ml. of dry acetonitrile is heated at reflux temperatures overnight. The solution is cooled and 35 ml. of diethyl ether added. The precipitated solids are collected and twice recrystallized from isopropanol-diethyl ether, 3.8 g., m.p. 193°-195° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04163745 |
| Source dataset | uspto-grants-1979_08 |
| ORD ID | ord-0acab4bbb1c44328b8b7d4b097046ffd |
| Source note | uspto-grants-1979_08 |