Ethyl 2,3-dibromopropionate → HCID 20395265, compound

HRID 261193Notes

Reaction equation

HRID 261193 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[C:5]([NH2:10])[CH:4]=1.Br[CH:12]([CH2:18]Br)[C:13]([O:15]CC)=[O:14]>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]2[O:9][CH:12]([C:13]([OH:15])=[O:14])[CH2:18][NH:10][C:5]=2[CH:4]=1

Participants

3

Reactant 2

HCID 97945Ethyl 2,3-dibromopropionateHCID 14191082-Amino-4-methoxyphenol

Product 1

HCID 20395265HCID 20395265, compound

Procedure

7B was treated with ethyl 2,3-dibromopropionate to form the ethyl ester of 6-methoxy-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid, and this was converted to 7, mp: 83°-85° C., by the procedures described in the other examples.

Sources & evidence

ORD record
ord-29fddbba20cb4452800470f02be50ab0
Source dataset
uspto-grants-1979_08
Patent number
US04164576

Reaction notes

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