反应详情

4-Chloro-3,5-dinitro-o-xylene (10.0 grams, 0.043 mole) and i-propylamine (10.1 grams, 0.17 mole) are mixed and refluxed for 12 hours using an efficient reflux condenser. The mixture is then cooled and poured into 100 ml. of 5% hydrochloric acid and extracted with diethyl ether. The ether extract is dried over magnesium sulfate. Removal of the drying agent and solvent leaves an orange oil which readily solidifies. The product is recrystallized from methanol to give 8.7 grams (80%) of an orange solid with melting point 69° C. to 70° C.

1. temperaturerefluxed for 12 hours
2. temperatureThe mixture is then cooled
3. additionpoured into 100 ml
4. extractionof 5% hydrochloric acid and extracted with diethyl ether
5. extractionThe ether extract
6. dry with materialis dried over magnesium sulfate
7. customRemoval of the drying agent and solvent
8. customleaves an orange oil which
9. customThe product is recrystallized from methanol