Ammonia → HCID 70563300, compound

HRID 261298Notes

Reaction equation

HRID 261298 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:14](Cl)=[O:15])[C:5]([CH2:11][O:12][CH3:13])=[CH:6][C:7]=1[N+:8]([O-:10])=[O:9].[NH3:17]>CCOCC>[Cl:1][C:2]1[CH:3]=[C:4]([C:14]([NH2:17])=[O:15])[C:5]([CH2:11][O:12][CH3:13])=[CH:6][C:7]=1[N+:8]([O-:10])=[O:9]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 86735828HCID 86735828, compound

Product 1

HCID 70563300HCID 70563300, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A sample of 4-chloro-α-methoxy-5-nitro-o-toluoyl chloride (1.5 g.) is added to 100 ml of ether saturated with ammonia. During the addition and for 15 minutes thereafter, the reaction temperature is kept below 20°. The precipitate solid is collected and washed well with water. The crude product (0.9) has an infrared compatible with the desired structure.

Workup

  1. additionDuring the addition
  2. customis kept below 20°
  3. customThe precipitate solid is collected
  4. washwashed well with water

Sources & evidence

ORD record
ord-341480b5bc14448d9db1877518277b29
Source dataset
uspto-grants-1979_08
Patent number
US04165231

Reaction notes

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