HuagongsheHuagongshe Chemistry Print Report · For research reference only
DL-Phenylalanine, methyl ester → (R)-Methyl 2-amino-3-phenylpropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | DL-Phenylalanine, methyl ester | HCID 75737 | — |
| Reactant | N-(Benzyloxycarbonyl)-L-aspartyl-L-phenylalanine methyl ester | HCID 10159630 | — |
| Product | (R)-Methyl 2-amino-3-phenylpropanoate | HCID 853474 | 62.3% |
Reaction Steps
Example 17 was repeated except for using DL-phenylalanine methyl ester instead of L-phenylalanine methyl ester to obtain 756 mg of an addition compound of N-benzyloxycarbonyl-L-aspartyl L-phenylalanine methyl ester and D-phenyl alanine methyl ester (1:1) (melting point: 105 to 111° C; yield: 62.3% based on N-benzyloxycarbonyl L-aspartic acid).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04165311 |
| Source dataset | uspto-grants-1979_08 |
| ORD ID | ord-830efca480624c2d84a62dcda9023651 |
| Source note | uspto-grants-1979_08 |