Toluene → Phenyl chloroformate

HRID 261468Notes

Reaction equation

HRID 261468 reaction equation
[Cl:1][C:2]([O-:4])=[O:3].[C:5]1(C)[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1>C1C=CC=CC=1>[C:5]1([O:3][C:2]([Cl:1])=[O:4])[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

Participants

4

Reactant 2

HCID 1140TolueneHCID 21226386Carbonochloridate

Product 1

HCID 15891Phenyl chloroformate

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Alternatively, a compound of formula II can be treated with a chloroformate, e.g., an alkylchloroformate or phenylchloroformate, at a temperature of 25°-125° C. in a solvent such as toluene or benzene to provide the corresponding N-alkoxycarbonyl or N-phenoxycarbonyl compound.

Sources & evidence

ORD record
ord-c463ebea49814c8980033cae58d70940
Source dataset
uspto-grants-1979_08
Patent number
US04166120

Reaction notes

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