Sulfuryl chloride → HCID 20394354, compound

HRID 261485Notes

Reaction equation

HRID 261485 reaction equation
[CH2:1]([N:5]([C:14]1[CH:18]=[CH:17][N:16]([CH3:19])[N:15]=1)[C:6]([CH:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1)=[O:7])[CH2:2][CH2:3][CH3:4].S(Cl)([Cl:23])(=O)=O>C1C=CC=CC=1>[CH2:1]([N:5]([C:14]1[C:18]([Cl:23])=[CH:17][N:16]([CH3:19])[N:15]=1)[C:6]([CH:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1)=[O:7])[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 24648Sulfuryl chlorideHCID 20394335HCID 20394335, compound

Product 1

HCID 20394354HCID 20394354, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

N-Butyl-N-(1-methylpyrazol-3-yl) cyclohexane carboxamide (1.3 g, 0.0049 m) in dry benzene (15 cc) was cooled at 0° C. while sulphuryl chloride (0.67 g, 0.0049 m) was added slowly. The cooling bath was then removed and the solution was kept at room temperature for 12 hours. The solvent was then evaporated and the residue crystalled from ether/petrol (40°-60° C.) as white prisms, 1.0 g, m.p. 110°-112° C.

Workup

  1. additionwas added slowly
  2. customThe cooling bath was then removed
  3. customThe solvent was then evaporated
  4. customcrystalled from ether/petrol (40°-60° C.) as white prisms, 1.0 g, m.p. 110°-112° C.

Sources & evidence

ORD record
ord-d2a26e2ad01d4d1789ed50428177af59
Source dataset
uspto-grants-1979_08
Patent number
US04166123

Reaction notes

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