HCID 53667781, compound → HCID 20394400, compound

HRID 261518Notes

Reaction equation

HRID 261518 reaction equation
[Cl:1][C:2]1[CH:21]=[CH:20][CH:19]=[C:18]([Cl:22])[C:3]=1[NH:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[CH:11]([OH:17])[C:12]([O:14]CC)=[O:13].ClC1C=CC=C(Cl)C=1NC1C=CC=CC=1C(O)C(OC)=O>>[Cl:1][C:2]1[CH:21]=[CH:20][CH:19]=[C:18]([Cl:22])[C:3]=1[NH:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[CH:11]([OH:17])[C:12]([OH:14])=[O:13]

Participants

3

Reactant 2

HCID 53667781HCID 53667781, compoundHCID 54370809HCID 54370809, compound

Product 1

HCID 20394400HCID 20394400, compoundYield 78%

Procedure

The same procedures as in the Step 4 of Example 1 were repeated except that 13.6 g of ethyl 2-(2,6-dichloroanilino)-phenylglycolate were employed instead of 13.0 g of methyl 2-(2,6-dichloroanilino)phenylglycolate, thereby yielding 9.7 g of 2-(2,6-dichloroanilino)phenylglycolic acid. m.p. 139°-141.5° C. Yield: 78% of theoretical amount

Sources & evidence

ORD record
ord-cb4c436c11fb40a59ce2975c15c51767
Source dataset
uspto-grants-1979_08
Patent number
US04166128

Reaction notes

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