Water → HCID 23677289, compound

HRID 261519Notes

Reaction equation

HRID 261519 reaction equation
[Cl:1][C:2]1[CH:19]=[CH:18][CH:17]=[C:16]([Cl:20])[C:3]=1[NH:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[CH:11]([OH:15])[C:12]([OH:14])=[O:13].[OH-].[Na+:22].O>C(O)C>[Cl:1][C:2]1[CH:19]=[CH:18][CH:17]=[C:16]([Cl:20])[C:3]=1[NH:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[CH:11]([OH:15])[C:12]([O-:14])=[O:13].[Na+:22]

Participants

5

Reactant 3

HCID 962WaterHCID 14798Sodium HydroxideHCID 20394400HCID 20394400, compound

Product 1

HCID 23677289HCID 23677289, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 6.24 g of 2-(2,6-dichloroanilino)phenylglycolic acid in 30 ml of ethanol were added 10 ml of a 5 N aqueous sodium hydroxide solution and the mixture was stirred at room temperature for 1 hour. Then, 20 ml of water were added, and the mixture was concentrated to have a volume of 30 ml. The concentrate was cooled and the solid thus deposited was recovered by filtration. Recrystallization from water gave sodium 2-(2,6-dichloroanilino)phenylglycolate. m.p. 101°-104° C.

Workup

  1. concentrationthe mixture was concentrated
  2. temperatureThe concentrate was cooled
  3. filtrationthe solid thus deposited was recovered by filtration
  4. customRecrystallization from water

Sources & evidence

ORD record
ord-909b0081ae804378a546ef2ae5cd8247
Source dataset
uspto-grants-1979_08
Patent number
US04166128

Reaction notes

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