反应详情

69 g of α-ethyl-α-methyl-dihydrocinnamic acid are added dropwise at 150°, within 5 minutes, to 700 g of polyphosphoric acid, while stirring. The reaction mixture is stirred at 160° for a further 10 minutes, is cooled to 100° and 100 cc of water are added dropwise. The reaction mixture is then poured on ice, extracted with ether, the ether extract is washed with water and dried over sodium sulphate. The 2-ethyl-2-methyl-1-indanone, obtained after evaporating the solvent, is purified by distillation. B.P. 137°-140° at 20 mm of Hg.

1. stirringThe reaction mixture is stirred at 160° for a further 10 minutes
2. temperatureis cooled to 100°
3. additionThe reaction mixture is then poured on ice
4. extractionextracted with ether
5. extractionthe ether extract
6. washis washed with water
7. dry with materialdried over sodium sulphate