Water → HCID 23337062, compound

HRID 261565Notes

Reaction equation

HRID 261565 reaction equation
[CH2:1]([O:3][C:4]1[CH:20]=[CH:19][C:7]2[S:8][C:9]3[CH:17]=[CH:16][CH:15]=[C:14]([Cl:18])[C:10]=3[CH2:11][C:12](=[O:13])[C:6]=2[CH:5]=1)[CH3:2].O>CO.C(Cl)(Cl)Cl>[CH2:1]([O:3][C:4]1[CH:20]=[CH:19][C:7]2[S:8][C:9]3[CH:17]=[CH:16][CH:15]=[C:14]([Cl:18])[C:10]=3[CH2:11][CH:12]([OH:13])[C:6]=2[CH:5]=1)[CH3:2]

Participants

5

Reactant 2

HCID 962WaterHCID 12687105HCID 12687105, compound

Product 1

HCID 23337062HCID 23337062, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 6212ChloroformSolvent

Procedure

An amount of 31.8 g of 2-ethoxy-9-chloro-10,11 -dihydrodibenzo[b,f]thiepin-11-one was dissolved in 200 ml of a mixed solvent of methanol and chloroform (5/1) and the mixture was stirred at room temperature for 2 hours and freed of the solvent to obtain the residue. To the resulting residue was added 100 ml of water and the mixture was extracted with chloroform. The extract was washed with water, dried over anhydrous sodium sulfate and freed of the solvent to obtain the residue.

Workup

  1. customto obtain the residue
  2. extractionthe mixture was extracted with chloroform
  3. washThe extract was washed with water
  4. dry with materialdried over anhydrous sodium sulfate
  5. customto obtain the residue

Sources & evidence

ORD record
ord-4dc78ed28a2c48ac8a3d942d054b690c
Source dataset
uspto-grants-1979_08
Patent number
US04166127

Reaction notes

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