Propionic anhydride → HCID 20394560, compound

Participants

Reaction Steps

Reaction of 4-(4-benzamidobutyl)-2-phenyl-5-oxazolone according to the procedure of Example 1 (ii) but using propionic anhydride in place of acetic anhydride yields 4,8-dibenzamidooctan-3-one which on hydrolysis according to the procedure of Example 1 (iii) gives 4,8-diaminooctan-3-one. Reaction of this product with potassium thiocyanate according to the procedure of Example 1 (iv) gives the title compound.

Provenance & Evidence