Sodium Carbonate → N-(3,5-di tert.butyl-4-hydroxyphenyl)cinnamamide

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Reaction Steps

N-(3,5-di tert.butyl-4-hydroxyphenyl)cinnamamide was prepared by adding a solution of 18.2 grams of cinnamoyl chloride in 50 milliliters of benzene to a solution of 2,6-di tert.butyl-4 -aminophenol prepared as described in Example 2 to which had been added 6 grams of sodium carbonate. The addition was accomplished in 30 minutes at 24° C. to 37° C. The mixture was stirred for 1 hour. The solid product was filtered, washed thoroughly with 2% hydrochloric acid, and dried. The yield was 17 grams of product which melted at 211° C. to 214° C.

Provenance & Evidence