HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzyl-1H-benzo[d]imidazol-2(3H)-one → 4-Benzyl-2-(1-benzyl-2,3-dihydro-benzimidazol-2-on-3-yl-methyl)-morpholine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzyl-1H-benzo[d]imidazol-2(3H)-one | HCID 736505 | — |
| Reactant | 4-Benzyl-2-(chloromethyl)morpholine | HCID 2801562 | — |
| Product | 4-Benzyl-2-(1-benzyl-2,3-dihydro-benzimidazol-2-on-3-yl-methyl)-morpholine hydrochloride | HCID 70601713 | 44.4% |
Reaction Steps
The condensation of 0.1 mol of 1-benzyl-2,3-dihydrobenzimidazol-2-one and 0.1 mol of 2-chloromethyl-4-benzyl-morpholine is carried out in accordance with the procedure of Example 1. 20 g of 4-benzyl-2-(1-benzyl-2,3-dihydro-benzimidazol-2-on-3-yl-methyl)-morpholine hydrochloride are obtained, m.p. 196° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04152434 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-3f107592ecb94dbd907cb890f68aebba |
| Source note | uspto-grants-1979_05 |