HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Benzyl-2-(chloromethyl)morpholine → 4-Benzyl-2-(1-methyl-5-methoxy-2,3-dihydrobenzimidazol-2-on-3-yl-methyl)-morpholine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Benzyl-2-(chloromethyl)morpholine | HCID 2801562 | — |
| Reactant | 5-methoxy-1-methyl-1H-benzo[d]imidazol-2(3H)-one | HCID 21321253 | — |
| Product | 4-Benzyl-2-(1-methyl-5-methoxy-2,3-dihydrobenzimidazol-2-on-3-yl-methyl)-morpholine hydrochloride | HCID 70601928 | 44.6% |
Reaction Steps
The condensation of 0.1 mol of 1-methyl-5-methoxy-2,3-dihydro-benzimidazol-2-one and 0.1 mol of 2-chloromethyl-4-benzyl-morpholine is carried out in accordance with the procedure of Example 1. 18 g of 4-benzyl-2-(1-methyl-5-methoxy-2,3-dihydrobenzimidazol-2-on-3-yl-methyl)-morpholine hydrochloride are obtained, m.p. 175° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04152434 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-9571532900a84b3a99b7a5aa91e08c80 |
| Source note | uspto-grants-1979_05 |