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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 261785Generated: October 25, 2026

2H-Benzimidazol-2-one, 1,3-dihydro-1-phenyl- → 4-Benzyl-2-(1-phenyl-2,3-dihydro-benzimidazol-2-on-3-yl-methyl)-morpholine

https://huagongshe.com/reaction/261785

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2H-Benzimidazol-2-one, 1,3-dihydro-1-phenyl-HCID 84657—
Reactant4-Benzyl-2-(chloromethyl)morpholineHCID 2801562—
Product4-Benzyl-2-(1-phenyl-2,3-dihydro-benzimidazol-2-on-3-yl-methyl)-morpholineHCID 70601820—

Reaction Steps

The condensation of 0.1 mol of 1-phenyl-2,3-dihydro-benzimidazol-2-one and 0.1 mol of 2-chloromethyl-4-benzyl-morpholine in accordance with the procedure (a) of Example 1 gives, after evaporation of the solvent under reduced pressure, a pale pink solid which melts at about 90° C. and which is used as such for the subsequent operations.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04152434
Source datasetuspto-grants-1979_05
ORD IDord-25b17f710bfa40f6b3f9d4a5c591d0cc
Source noteuspto-grants-1979_05