反应详情

o-Chlorobenzaldehyde (0.20 mole) is treated with 3-chloro-2-methyl aniline (0.20 mole) with vigorous stirring in a 1 l. Erlenmeyer Flask. After 15 mins., 33 cc of 95% ethanol is added and the reaction mixture is stirred vigorously for an additional 5 mins. The reaction mixture is left standing at room temperature for 10 mins., then it is placed in an ice bath for 0.5 hr. The crystals which formed are collected, washed with 95% ethanol, and air dried. Recrystallization from 85% ethanol gives N-(o-Chlorobenzylidene)-2-methyl-3-chloroaniline. m.p. 83°-85° C.

1. stirringthe reaction mixture is stirred vigorously for an additional 5 mins
2. waitThe reaction mixture is left
3. waitstanding at room temperature for 10 mins
4. wait, then it is placed in an ice bath for 0.5 hr
5. customThe crystals which formed
6. customare collected
7. washwashed with 95% ethanol, and air
8. customdried
9. customRecrystallization from 85% ethanol