1073-38-7 → HCID 86736510, compound

HRID 261872Notes

Reaction equation

HRID 261872 reaction equation
S[C:2]1[C:3](=[O:9])[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1.S[C:11]1C2C=CC=CC=2C=CC(=O)[CH:12]=1.NC1C2C=NC=CC=2C=CC(=O)C=1>>[CH:11]1[C:8]2[CH2:7][CH2:6][CH:5]=[CH:4][C:3](=[O:9])[C:2]=2[CH:12]=1

Participants

4

Reactant 3

HCID 125576901073-38-7HCID 21321474HCID 21321474, compoundHCID 21321481HCID 21321481, compound

Product 1

HCID 86736510HCID 86736510, compound

Procedure

By following serially the procedures of Examples 1 and 2 but replacing 2-mercapto-2,4,6-cycloheptatrien-1-one with an equivalent amount of 5-mercapto-7H-benzocyclohepten-7-one, 9-amino-7H-cyclohepta[c]pyridin-7-one, 5-mercapto-3H,-6,7-dihydrocyclobutacyclohepten-3-one, 1-ethylamino-3H-6,7,8,9,10,11-hexahydrocycloheptacycloocten-3-one and 5-mercapto-3H-6,7,8,9,10,11,12,13-octahydrocycloheptacyclodecen-3-one, the following compounds are obtained respectively: [(7-oxo-7H-benzocyclohepten-5-yl)thio]oxoacetic acid ethyl ester (l; R1, R5, and R6 = H; R2 = S--CO--COOC2H5 ; and R3 and R4 together form a --CH=CH--CH=CH-- chain), [(7-oxo-7H-cyclohepta[c]pyridin-9-yl)-amino]oxo-acetic acid ethyl ester (I; R1, R5 and R6 = H; R2 = NC2H5 --CO--COOC2H5 ; and R3 and R4 together form a --CH=CH--N=CH-- chain). [(3-oxo-3H-6,7-dihydrocyclobutacyclohepten-5-yl)thio]oxo-acetic acid ethyl ester (I; R1, R5 and R6 = H; R2 = S--CO--COOC2H5 ; and R3 and R4 together form a --CH2CH2 -- chain), [N-(3-oxo-3H-6,7,8,9,10,11-hexahydrocycloheptacycloocten-1-yl)ethylamino]oxo-acetic acid ethyl ester (I; R1, R2 and R6 = H; R3 and R4 together form a --(CH2)6 chain; and R5 = NC2H5 --CO--COOC2H 5) and [(3-oxo-3H-6,7,8,9,10,11,12,13-octahydrocycloheptacyclodecen-5-yl)thio]oxo-acetic acid ethyl ester (I; R1, R5 and R6 = H; R2 = S--CO--COOC2H5 ; and R3 and R4 together form a --(CH2)8 -- chain).

Sources & evidence

ORD record
ord-0c308f299efd4872858f34fbc6e1f580
Source dataset
uspto-grants-1979_05
Patent number
US04152457

Reaction notes

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