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HRID261883

反应详情

EQUATION

反应方程式

HRID 261883 的结构方程式

REACTANTS

反应物

2
结构：O=C(Cl)c1cccc(Cl)c1
HCID69252

Benzoyl chloride, 3-chloro-

C7H4Cl2O

结构：CN(C)C1CCCCC1N
HCID12447266

N~1~,N~1~-Dimethylcyclohexane-1,2-diamine

C8H18N2

PRODUCTS

生成物

1
结构：CN(C)[C@@H]1CCCC[C@H]1NC(=O)c1cccc(Cl)c1
HCID53979363

未命名化合物

收率 62%

PROCEDURE

实验过程

This titled amide was prepared by general procedure B from 2-(dimethylamino)cyclohexylamine and 3-chlorobenzoyl chloride. The crude product was crystallized from ether-petroleum ether (30°-60°); yield 62%, m.p. 112°-113°. The analytical sample melted at 112.5°-113.5°. uv sh 217 nm (ε 11,850); sh 226 (9,550); sh 227 (1,200); sh 287 (623). ir NH/=CH 3320, 3070; N-alkyl 2760; C=O 1635; C=C 1595, 1570; l amide II 1545. NMR in CDCl3 (100 MHz) was in accord. Mass spectrum M+ 280.

WORKUP

后处理

  1. customThe crude product was crystallized from ether-petroleum ether (30°-60°)