3,5-Dimethylbenzoyl Chloride → cis-N-[2-(3-acetyloxy-1-pyrrolidinyl)cyclohexyl]-3,5-dimethylbenzamide

HRID 261889Notes

Reaction equation

HRID 261889 reaction equation
[C:1]([O:4][CH:5]1[CH2:9][CH2:8][N:7]([C@H:10]2[CH2:15][CH2:14][CH2:13][CH2:12][C@H:11]2[NH2:16])[CH2:6]1)(=[O:3])[CH3:2].[CH3:17][C:18]1[CH:19]=[C:20]([CH:24]=[C:25]([CH3:27])[CH:26]=1)[C:21](Cl)=[O:22]>>[C:1]([O:4][CH:5]1[CH2:9][CH2:8][N:7]([C@H:10]2[CH2:15][CH2:14][CH2:13][CH2:12][C@H:11]2[NH:16][C:21](=[O:22])[C:20]2[CH:24]=[C:25]([CH3:27])[CH:26]=[C:18]([CH3:17])[CH:19]=2)[CH2:6]1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 810883,5-Dimethylbenzoyl ChlorideHCID 54343056cis-N-[2-(3-acetyloxy-1-pyrrolidinyl)cyclohexyl]amine

Product 1

HCID 54468108cis-N-[2-(3-acetyloxy-1-pyrrolidinyl)cyclohexyl]-3,5-dimethylbenzamide

Procedure

Following the procedure of Example 1b, using cis-N-[2-(3-acetyloxy-1-pyrrolidinyl)cyclohexyl]amine and 3,5-dimethylbenzoyl chloride there is obtained as product cis-N-[2-(3acetyloxy-1-pyrrolidinyl)cyclohexyl]-3,5-dimethylbenzamide.

Sources & evidence

ORD record
ord-329621122f9a4a75a186c52f1231d9cd
Source dataset
uspto-grants-1979_05
Patent number
US04152459

Reaction notes

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