HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dichlorobenzoic acid → N-methyl-N-[2-(3-hydroxy-1-pyrrolidinyl)cyclohexyl]-3,4-dichlorobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dichlorobenzoic acid | HCID 5817 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 2-(3-Hydroxy-1-pyrrolidinyl)cyclohexylamine | HCID 62941729 | — |
| Product | N-methyl-N-[2-(3-hydroxy-1-pyrrolidinyl)cyclohexyl]-3,4-dichlorobenzamide | HCID 23349811 | — |
Reaction Steps
Following the procedure of Example 1a, using trans-N-methyl-N-[2-(3-hydroxy-1-pyrrolidinyl)cyclohexylamine, carbonyldiimidazole] and 3,4-dichlorobenzoic acid there is obtained N-methyl-N-[2-(3-hydroxy-1-pyrrolidinyl)cyclohexyl]-3,4-dichlorobenzamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04152459 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-4588e6aa34e34c93a7fcf532860d1da3 |
| Source note | uspto-grants-1979_05 |