HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → Cyclopentylacetyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Cyclopentylacetic acid | HCID 71606 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Cyclopentylacetyl chloride | HCID 3485182 | — |
Reaction Steps
To a solution of 50 g. of cyclopentaneacetic acid containing 2.9 ml of N,N-dimethylformamide is added dropwise with stirring, 51 g. of thionyl chloride over a period of 15 minutes. After stirring for an additional 60 minutes excess thionyl chloride is removed in vacuo and the residual oil is distilled to give 55.4 g. (97%) of product, b.p. 57°-58° C. (10 mm.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04152524 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-f97d8ca0a76a4fbab157dc8a7198fda8 |
| Source note | uspto-grants-1979_05 |