Sulfuric Acid → HCID 21319835, compound

HRID 262029Notes

Reaction equation

HRID 262029 reaction equation
[CH2:1]([S:3][C:4]1[S:5][C:6]([C:10](=[S:12])[NH2:11])=[C:7]([NH2:9])[N:8]=1)[CH3:2].S(=O)(=O)(O)O.BrBr>>[NH2:11][C:10]1[S:12][N:9]=[C:7]2[N:8]=[C:4]([S:3][CH2:1][CH3:2])[S:5][C:6]=12

Participants

4

Reactant 3

HCID 1118Sulfuric AcidHCID 24408BromineHCID 21319833HCID 21319833, compound

Product 1

HCID 21319835HCID 21319835, compoundYield 87%

Procedure

27.1 parts of 2-ethylmercapto-4-amino-5-thiocarbamoylthiazole are reacted with 270 parts of sulfuric acid and 0.5 part of bromine as described in Example 1(b). 23.4 parts of 3-amino-5-ethylmercapto-thiazolo-(4,5-c)-isothiazole (87% of theory) of melting point 131°-134° C. are obtained.

Sources & evidence

ORD record
ord-4b42210e853c44ff9e6521b35ba8a56d
Source dataset
uspto-grants-1979_05
Patent number
US04153607

Reaction notes

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