HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 3-Amino-5-pyrrolidino-thiazolo-(4,5-c)-isothiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 2-Pyrrolidino-4-amino-5-thiocarbamoylthiazole | HCID 12526354 | — |
| Product | 3-Amino-5-pyrrolidino-thiazolo-(4,5-c)-isothiazole | HCID 12526370 | 91% |
Reaction Steps
11 parts of 2-pyrrolidino-4-amino-5-thiocarbamoyl-thiazole in 70 parts of sulfuric acid are oxidized with 0.5 part of bromine by the method described in Example 1(b). 10 parts of 3-amino-5-pyrrolidino-thiazolo-(4,5-c)-isothiazole (91% of theory) of melting point 270°-273° C. are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04153607 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-9e69aae3392a4552a55082eb4aa8513e |
| Source note | uspto-grants-1979_05 |