Benzoic acid, 2-[(1-ethyl-2-methyl-1H-indol-3-yl)carbonyl]- → Phthalide

HRID 262041Notes

Reaction equation

HRID 262041 reaction equation
[C:1]([C:4]1[CH:23]=[CH:22][CH:21]=[CH:20][C:5]=1[C:6](C1C2C(=CC=CC=2)N(CC)C=1C)=[O:7])(O)=[O:2].C(C1C=CC=CC=1C(C1C2C(=CC=CC=2)N(CCCCC)C=1C)=O)(O)=O>>[C:1]1([C:4]2[C:5](=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH2:6][O:7]1)=[O:2]

Participants

3

Reactant 2

HCID 3084978Benzoic acid, 2-[(1-ethyl-2-methyl-1H-indol-3-yl)carbonyl]-HCID 205651483-(2'-Carboxybenzoyl)-1-n-pentyl-2-methyl-indole

Product 1

HCID 6885Phthalide

Procedure

If the 3-(2'-carboxybenzoyl)-1-ethyl-2-methyl-indole in Example 1 is replaced by an equimolar amount of 3-(2'-carboxybenzoyl)-1-n-pentyl-2-methyl-indole, with the procedure otherwise being as described in Example 1, there is obtained 3.6 g of a phthalide compound of the formula ##STR15## which melts at 162°-163° C. The colour former develops on silton clay a blue colour of λ max. 600 nm.

Sources & evidence

ORD record
ord-87395fba40eb4478a660557c5a4f5db5
Source dataset
uspto-grants-1979_05
Patent number
US04153609

Reaction notes

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