HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 2,2,6,6-Tetramethyl-4-hydroxypiperidine-4-carboxylic acid hydrazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 4-Piperidinecarboxylic acid, 4-hydroxy-2,2,6,6-tetramethyl-, methyl ester | HCID 106691 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2,2,6,6-Tetramethyl-4-hydroxypiperidine-4-carboxylic acid hydrazide | HCID 70593441 | — |
Reaction Steps
16.2 parts of 2,2,6,6-tetramethyl-4-hydroxypiperidine-4-carboxylic acid methyl ester (according to German Patent No. 91,122), 5 parts of hydrazine hydrate and 20 parts of methanol are boiled under reflux for 10 hours and the methanol is subsequently distilled off. The residue is recrystallised from cyclohexane. Yield: 15.3 parts of 2,2,6,6-tetramethyl-4-hydroxypiperidine-4-carboxylic acid hydrazide melting at 121° to 123° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04153596 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-2b614d09f6a849fe86bd116c591b1bca |
| Source note | uspto-grants-1979_05 |