HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propargylamine → 1-(2-propynyl)-3-(5,6,7,8-tetrahydro-8-oxo-4H-cyclohepta[b]thien-4-yl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propargylamine | HCID 239041 | — |
| Reactant | Bis-(1H-imidazol-2-YL)-methanone | HCID 5250894 | — |
| Reactant | HCID 21319845 | HCID 21319845 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-(2-propynyl)-3-(5,6,7,8-tetrahydro-8-oxo-4H-cyclohepta[b]thien-4-yl)urea | HCID 21319856 | — |
Reaction Steps
A sample of 11 grams of carbonyl diimidazole in 50 ml. of methylene chloride is stirred and an equivalent amount of 5,6,7,8-tetrahydro-8-oxo-4H-cyclohepta[b]thiophen-4-amine in 50 ml. of methylene chloride is added. After one hour, 3.74 grams of propargylamine in 50 ml. of methylene chloride is added. The mixture is stirred at room temperature for 3 hours and the title compound is collected by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04153611 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-a39ac8fd20ff411fa573d6c545ba4d12 |
| Source note | uspto-grants-1979_05 |