HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → 2-Chloro-1-(3-methoxyphenyl)-indole 3-carboxylic acid morpholide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | HCID 53923702 | HCID 53923702 | — |
| Product | 2-Chloro-1-(3-methoxyphenyl)-indole 3-carboxylic acid morpholide | HCID 53739927 | — |
Reaction Steps
This compound was prepared from 2-chloro-1(3-methoxyphenyl)-indole-3-carboxylic acid chloride and morpholine to yield 2-chloro-1-(3-methoxyphenyl)-indole 3-carboxylic acid morpholide which was reacted with N-methyl-piperazine according to Example 42. The yield of amorphous product was 85% of the theoretical yield; the amorpheus hydrochloride had a decomposition point above 160° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04148895 |
| Source dataset | uspto-grants-1979_04 |
| ORD ID | ord-44b1dae9499a424cbf524879c7e936d2 |
| Source note | uspto-grants-1979_04 |