Ethanol, 2-chloro-, 1-(4-methylbenzenesulfonate) → HCID 12672371, compound

HRID 262063Notes

Reaction equation

HRID 262063 reaction equation
[C:1]([NH:4][C:5]1[C:6]([OH:18])=[C:7]([O:16][CH3:17])[C:8]2[O:12][CH:11]=[CH:10][C:9]=2[C:13]=1[O:14][CH3:15])(=[O:3])[CH3:2].S(O[CH2:30][CH2:31][Cl:32])(C1C=CC(C)=CC=1)(=O)=O>O>[C:1]([NH:4][C:5]1[C:6]([O:18][CH2:30][CH2:31][Cl:32])=[C:7]([O:16][CH3:17])[C:8]2[O:12][CH:11]=[CH:10][C:9]=2[C:13]=1[O:14][CH3:15])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 6639Ethanol, 2-chloro-, 1-(4-methylbenzenesulfonate)HCID 12672367HCID 12672367, compound

Product 1

HCID 12672371HCID 12672371, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of 25.1 g (0.1 mole) of 5-acetamido 4,7-dimethoxy 6-hydroxy benzofuran in 15 ml of a 50% aqueous solution of soda was brought to 90° C. and 21 g (0.1 mole) of 2-chloro ethanol tosylate was slowly added, it was ketp at 90° C. for 2 hours, diluted in 1 l of water, filtered and recrystallized in ethanol.

Workup

  1. customwas brought to 90° C.
  2. customat 90° C.
  3. customfor 2 hours
  4. filtrationfiltered
  5. customrecrystallized in ethanol

Sources & evidence

ORD record
ord-27d4654d8f9c4fc58142ff8662e7d8f2
Source dataset
uspto-grants-1979_05
Patent number
US04153620

Reaction notes

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