HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aspirin → Salicylic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aspirin | HCID 2244 | — |
| Reactant | Salicylamide | HCID 5147 | — |
| Reactant | HCID 21319996 | HCID 21319996 | — |
| Product | Salicylic Acid | HCID 338 | — |
| Product | Salicylamide | HCID 5147 | — |
Reaction Steps
The following experiments illustrate (A) the reduced gastric toxicity of 2-(carbamoyl)phenyl-2-acetoxybenzoate relative to a physical mixture of aspirin and salicylamide and (B) the in vivo hydrolysis of 2-(carbamoyl)phenyl-2-acetoxybenzoate to give plasma concentrations of salicylic acid and salicylamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04153691 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-2aba2e29f55c4639b0f13c47850e352e |
| Source note | uspto-grants-1979_05 |