反应详情

Following the procedure of Example 1 but starting with 5-amino-3-methylisoquinoline (5.7 g) and (R)-3-methylthio-9,9a-dihydrothiazolo[3,4-a]indolium iodide (11.4 g), (R)-3-[(3-methylisoquinol-5-yl)imino]-9,9a-dihydrothiazolo[3,4-a]indole (7.3 g) is obtained, after recrystallisation from ethanol, in the form of white crystals melting at 181° C. [α]D20 =+92.0±1.5° (c=1, chloroform)