HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Ethylisoquinolin-5-amine → (RS)-3-[(3-ethylisoquinol-5-yl)imino]-9,9a-dihydrothiazolo[3,4-a]indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Ethylisoquinolin-5-amine | HCID 21320144 | — |
| Reactant | (RS)-3-Methylthio-9,9a-dihydrothiazolo[3,4-a]indolium iodide | HCID 21320148 | — |
| Product | (RS)-3-[(3-ethylisoquinol-5-yl)imino]-9,9a-dihydrothiazolo[3,4-a]indole | HCID 21320153 | 70.6% |
Reaction Steps
Following the procedure of Example 1 but starting with 5-amino-3-ethylisoquinoline (3.3 g) and (RS)-3-methylthio-9,9a-dihydrothiazolo[3,4-a]indolium iodide (6.3 g), (RS)-3-[(3-ethylisoquinol-5-yl)imino]-9,9a-dihydrothiazolo[3,4-a]indole (4.4 g) is obtained, after recrystallisation from ethanol (40 cc), in the form of white crystals melting at 142° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04153699 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-ea91d975393649b59bf779dfd2616974 |
| Source note | uspto-grants-1979_05 |