HuagongsheHuagongshe Chemistry Print Report · For research reference only
Urea → 2-Hydroxy-5-[1-hydroxy-2-(t-butylamino)ethyl]-benzeneacetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Urea | HCID 1176 | — |
| Reactant | Tert-Butylamine | HCID 6385 | — |
| Reactant | N-(1,1-Dimethylethyl)benzenamine | HCID 254260 | — |
| Reactant | 5-[N-(t-butylamino)glycyl]-2-hydroxyphenylacetonitrile | HCID 21325157 | — |
| Product | 2-Hydroxy-5-[1-hydroxy-2-(t-butylamino)ethyl]-benzeneacetonitrile | HCID 21325147 | — |
Reaction Steps
The procedure of Example 1(c) is repeated with substitution of an equimolar amount of t-butylamine for phenyl-t-butylamine in that example. The resulting aminoketone, 5-[N-(t-butylamino)glycyl]-2-hydroxyphenylacetonitrile is reduced according to the procedure of Example 1(d) to yield 2-hydroxy-5-[1-hydroxy-2-(t-butylamino)ethyl]-benzeneacetonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04148908 |
| Source dataset | uspto-grants-1979_04 |
| ORD ID | ord-aec84fb4c016461bbde1960083f72835 |
| Source note | uspto-grants-1979_04 |