HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-Chloroethyl)-N-methylbenzylamine hydrochloride → 7-[2-(N-benzyl-N-methylamino)ethoxy]-2,2-dimethyl-4-(2-naphthyl)-2H-chromene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-Chloroethyl)-N-methylbenzylamine hydrochloride | HCID 12822620 | — |
| Reactant | 2,2-Dimethyl-4-(naphthalen-2-yl)-2H-1-benzopyran-7-ol | HCID 20570540 | — |
| Product | 7-[2-(N-benzyl-N-methylamino)ethoxy]-2,2-dimethyl-4-(2-naphthyl)-2H-chromene | HCID 20570503 | 49% |
Reaction Steps
Reaction of N-benzyl-N-(2-chloroethyl)methylamine hydrochloride with 2,2-dimethyl-4-(2-naphthyl)-2H-chromen-7-ol by an analogous method to that described in Preparation 18 (c) gave the title compound (49%) as a colourless oil, The hydrochloride salt had m.p. 112°-115° C. decomposed.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04153617 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-b2b9cc0439464ad8b8c3156fd83dda23 |
| Source note | uspto-grants-1979_05 |