2-Amino-5-(2-aminoethyl)thiomethyl-1,3,4-thiadiazole → HCID 178433304, compound
Reaction equation
[NH2:1][C:2]1[S:3][C:4]([CH2:7][S:8][CH2:9][CH2:10][NH2:11])=[N:5][N:6]=1.[C:12]([C:14]([C:29]#[N:30])=[C:15](SC)[NH:16][CH2:17][CH2:18][S:19][CH2:20][C:21]1[NH:25][CH:24]=[N:23][C:22]=1[CH3:26])#[N:13]>>[C:12]([C:14]([C:29]#[N:30])=[C:15]([NH:11][CH2:10][CH2:9][S:8][CH2:7][C:4]1[S:3][C:2]([NH2:1])=[N:6][N:5]=1)[NH:16][CH2:17][CH2:18][S:19][CH2:20][C:21]1[NH:25][CH:24]=[N:23][C:22]=1[CH3:26])#[N:13]Participants
3
Procedure
By the procedure of Example 24(iii) reacting 2-amino-5-[(2-aminoethyl)thiomethyl]-1,3,4-thiadiazole with 1,1-dicyano-2-methylthio-2-[2-((4-methyl-5-imidazolyl)methylthio)ethylamino]ethylene, gives the title compound.
Sources & evidence
- ORD record
- ord-69e4ed9e6b0742e2b053e31a90516234
- Source dataset
- uspto-grants-1979_05
- Patent number
- US04153704
Reaction notes
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