反应详情

To a solution of 3.0 g. (0.0126 mole) of 7-(2-hydroxyethyl)-3-phenylbenzofuran in 50 ml. of dichloromethane is added dropwise 2.1 g. of bromine. After stirring for five minutes the mixture is evaporated, benzene is added to the residue and it is evaporated again. The residue is mixed with petroleum ether and crystallizes. Recrystallization from hexane gives 2-bromo-7-(2-hydroxyethyl)-3-phenylbenzofuran, m.p. 108°-112° C.

1. customis evaporated
2. additionbenzene is added to the residue and it
3. customis evaporated again
4. additionThe residue is mixed with petroleum ether
5. customcrystallizes
6. customRecrystallization from hexane