Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 262270Generated: November 1, 2026

3,4-Dichlorobenzoic acid → N-methyl-N-[2-(3-hydroxy-1-pyrrolidinyl)cyclohexyl]-3,4-dichlorobenzamide

https://huagongshe.com/reaction/262270

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-Dichlorobenzoic acidHCID 5817—
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
Reactant2-(3-Hydroxy-1-pyrrolidinyl)cyclohexylamineHCID 62941729—
ProductN-methyl-N-[2-(3-hydroxy-1-pyrrolidinyl)cyclohexyl]-3,4-dichlorobenzamideHCID 23349811—

Reaction Steps

Following the procedure of Example 1a, using trans-N-methyl-N-[2-(3-hydroxy-1-pyrrolidinyl)cyclohexylamine, carbonyldiimidazole and 3,4-dichlorobenzoic acid there is obtained N-methyl-N-[2-(3-hydroxy-1-pyrrolidinyl)-cyclohexyl]-3,4-dichlorobenzamide

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04153717
Source datasetuspto-grants-1979_05
ORD IDord-4aef3fda2e68497cbe2952a64df2bd2d
Source noteuspto-grants-1979_05