HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Lysine → Nalpha-(4-carboxy-2-methylbutanoyl)-L-lysine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Lysine | HCID 5962 | — |
| Reactant | benzyl (2S)-2-aminopropanoate | HCID 726858 | — |
| Reactant | benzyl (2S)-2-amino-6-(phenylmethoxycarbonylamino)hexanoate | HCID 7269426 | — |
| Reactant | Nalpha-(4-methoxycarbonyl-2-methylbutanoyl)-L-lysine | HCID 22804617 | — |
| Reactant | Nalpha-(4-methoxycarbonyl-2-methylbutanoyl)-Nepsilon-benzyloxycarbonyl-L-lysine benzyl ester | HCID 86736432 | — |
| Product | Nalpha-(4-carboxy-2-methylbutanoyl)-L-lysine | HCID 22804611 | — |
Reaction Steps
By substituting Nε -benzyloxycarbonyl-L-lysine benzyl ester for the L-alanine benzyl ester in the procedure of Example 23 and then treating the product by the procedure of Examples 24 and 26, Nα -(4-methoxycarbonyl-2-methylbutanoyl)-Nε -benzyloxycarbonyl-L-lysine benzyl ester, Nα -(4-methoxycarbonyl-2-methylbutanoyl)-L-lysine and Nα -(4-carboxy)-2-methylbutanoyl)-L-lysine are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04153725 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-edb5558598fe4bb1869d0dc23ea36e0c |
| Source note | uspto-grants-1979_05 |