HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-Benzyl 2-amino-3-(4-hydroxyphenyl)propanoate → N-(4-Carboxy-2-methylbutanoyl)-L-tyrosine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-Benzyl 2-amino-3-(4-hydroxyphenyl)propanoate | HCID 104541 | — |
| Reactant | benzyl (2S)-2-aminopropanoate | HCID 726858 | — |
| Reactant | N-(4-methoxycarbonyl-2-methylbutanoyl)-L-tyrosine | HCID 54358394 | — |
| Reactant | N-(4-methoxycarbonyl-2-methylbutanoyl)-L-tyrosine benzyl ester | HCID 54526057 | — |
| Product | N-(4-Carboxy-2-methylbutanoyl)-L-tyrosine | HCID 54098449 | — |
Reaction Steps
By substituting L-tyrosine benzyl ester for the L-alanine benzyl ester in the procedure of Example 23, and then treating the product by the procedure of Examples 24 and 26, N-(4-methoxycarbonyl-2-methylbutanoyl)-L-tyrosine benzyl ester, N-(4-methoxycarbonyl-2-methylbutanoyl)-L-tyrosine, and N-(4-carboxy-2-,ethylbutanoyl)-L-tyrosine are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04153725 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-916a169438784c9694befe85ceba0b90 |
| Source note | uspto-grants-1979_05 |