HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Ethyl 4-(2-methylphenyl)-3-oxobutanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sodium ethoxide | HCID 2723922 | — |
| Reactant | Ethyl 2-acetyl-4-(2-methylphenyl)-3-oxobutanoate | HCID 21325237 | — |
| Solvent | Water | HCID 962 | — |
| Product | Ethyl 4-(2-methylphenyl)-3-oxobutanoate | HCID 21325235 | — |
Reaction Steps
Following the method of Hunsdiecker [Berichte, 75, 454 (1942)], 26 parts of ethyl 2-acetyl-4-(2-methylphenyl)-3-oxobutanoate was stirred for 10 hours at room temperature with 100 parts ethanol and 6.8 parts of sodium ethoxide. The mixture was diluted with water and extracted with ether. The solvent was then evaporated to give ethyl 4-(2-methylphenyl)-3-oxobutanoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04148918 |
| Source dataset | uspto-grants-1979_04 |
| ORD ID | ord-9a083714fcfe4da197ac1521891f6029 |
| Source note | uspto-grants-1979_04 |