Acetone → HCID 21320510, compound

HRID 262282Notes

Reaction equation

HRID 262282 reaction equation
[CH2:1]([N:3]1[C:7]2=[N:8][CH:9]=[C:10]([C:14]([NH2:16])=[O:15])[C:11]([NH:12][NH2:13])=[C:6]2[CH:5]=[N:4]1)[CH3:2].[CH3:17][C:18]([CH3:20])=O>>[CH2:1]([N:3]1[C:7]2=[N:8][CH:9]=[C:10]([C:14]([NH2:16])=[O:15])[C:11]([NH:12][N:13]=[C:18]([CH3:20])[CH3:17])=[C:6]2[CH:5]=[N:4]1)[CH3:2]

Participants

3

Reactant 2

HCID 180AcetoneHCID 21320508HCID 21320508, compound

Product 1

HCID 21320510HCID 21320510, compound

Procedure

14 g. of well pulverized 1-ethyl-4-hydrazino-1H-pyrazolo[3,4-b]pyridine-5-carboxamide (0.0635 mol.) are dissolved in 500ml. of anhydrous acetone and the solution is allowed to stand overnight. Then excess acetone is removed in vacuo and the residual 1-ethyl-4-[2-(1-methylethylidene)hydrazino]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide is recrystallized from ethyl acetate, m.p. 217°-218°, yield 9.75 g. (59%).

Workup

  1. customThen excess acetone is removed in vacuo
  2. customthe residual 1-ethyl-4-[2-(1-methylethylidene)hydrazino]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide is recrystallized from ethyl acetate, m.p. 217°-218°, yield 9.75 g

Sources & evidence

ORD record
ord-e64d8c6a54f34bf7b4aae64d55522ccd
Source dataset
uspto-grants-1979_05
Patent number
US04153796

Reaction notes

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