HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → N-acetyl-3-phenylindoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3-phenyl-2,3-dihydro-1H-indole | HCID 10932353 | — |
| Product | N-acetyl-3-phenylindoline | HCID 15428722 | — |
Reaction Steps
1.0 G of 3-phenylindoline was dissolved in 10 ml of acetic anhydride at room temperature. After 10 minutes, the reaction mixture was poured into 100 ml of water, slightly basified with aqueous sodium hydroxide and extracted with methylene chloride. After removal of the methylenechloride, the residue was recrystallized from cyclohexane to give 1.15 g of the desired N-acetyl-3-phenylindoline which was found to have a 106°-7° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04153789 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-fd9bb74308fb497badfb14f6bc31f721 |
| Source note | uspto-grants-1979_05 |