HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Diisopropylamino)ethyl chloride → alpha-(o-Chlorophenyl)-alpha-[2-(diisopropylamino)ethyl]-alpha-[2-(dimethylamino)ethyl]acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Diisopropylamino)ethyl chloride | HCID 7312 | — |
| Reactant | 2-Chloro-N,N-dimethylethylamine | HCID 7901 | — |
| Reactant | 4-Diisopropylamino-2-phenyl-butyronitrile | HCID 12612210 | — |
| Reactant | 2-(2-Chlorophenyl)-4-(diisopropylamino)butanenitrile | HCID 12612211 | — |
| Product | alpha-(o-Chlorophenyl)-alpha-[2-(diisopropylamino)ethyl]-alpha-[2-(dimethylamino)ethyl]acetonitrile | HCID 12612244 | — |
Reaction Steps
Substitution of equivalent quantities of α-(o-chlorophenyl)-α-[2-(diisopropylamino)ethyl]acetonitrile and 2-chloro-N,N-dimethylethylamine for α-[2-(diisopropylamino)ethyl]-α-phenylacetonitrile and 2-chloro-N,N-diisopropylethylamine called for respectively in the procedure of Example 2, Method B, there is obtained α-(o-chlorophenyl)-α-[2-(diisopropylamino)ethyl]-α-[2-(dimethylamino)ethyl]acetonitrile, as an oil boiling at about 160°-165° C. at 0.5 mm. pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04153797 |
| Source dataset | uspto-grants-1979_05 |
| ORD ID | ord-1b9992dd39f44f7a876733e91ae42b6b |
| Source note | uspto-grants-1979_05 |