4-Diisopropylamino-2-phenyl-butyronitrile → HCID 12612233, compound

HRID 262319Notes

Reaction equation

HRID 262319 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[CH:9]([CH2:12][CH2:13][N:14]([CH:18]([CH3:20])[CH3:19])[CH:15]([CH3:17])[CH3:16])[C:10]#[N:11].[CH:21]([N:24]([CH:36]([CH3:38])[CH3:37])[CH2:25][CH2:26]C(C1C=CC=CC=1)C#N)([CH3:23])[CH3:22]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[C:9]([CH2:26][CH2:25][N:24]([CH:36]([CH3:38])[CH3:37])[CH:21]([CH3:23])[CH3:22])([CH2:12][CH2:13][N:14]([CH:18]([CH3:20])[CH3:19])[CH:15]([CH3:16])[CH3:17])[C:10]#[N:11]

Participants

3

Reactant 2

HCID 126122104-Diisopropylamino-2-phenyl-butyronitrileHCID 12612217HCID 12612217, compound

Product 1

HCID 12612233HCID 12612233, compound

Procedure

Substitution of an equivalent quantity of the preceding acetonitrile for α-[2-(diisopropylamino)ethyl]-α-phenylacetonitrile called for in Example 2, Method B and substantial repetition of the procedure detailed in that example, affords α-(2,6-dichlorophenyl)-α,α-bis[2-(diisopropylamino)ethyl]acetonitrile, as an oil boiling at about 180°-185° C. at 0.3 mm. pressure.

Sources & evidence

ORD record
ord-79430a6f9e1046178d3468fe75be150d
Source dataset
uspto-grants-1979_05
Patent number
US04153797

Reaction notes

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